Venture Investing

We fuel growth by combining leadership recruiting and the capital companies need to scale.

Most firms back companies with money. Others help them find leaders. We do both - because the right team is the real growth engine. By combining executive recruiting with venture capital, we help companies scale faster, stronger, and smarter.

Portfolio

Industry
Location
Year
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Company
Year
Background
Antria/Rezolute
Company
Industry:
BioTech
Location:
San Francisco
Year
2017
,

Background

Develops Ersodetug, a first-in-class insulin-receptor modulating antibody designed to treat congenital hyperinsulinism and tumor-related hyperinsulinism by preventing recurrent, dangerous hypoglycemia.

ArtLifting PBC
Company
Industry:
Social Enterprise
Location:
Boston
Year
2016
,

Background

Empowers artists impacted by homelessness or disability through art commerce and corporate partnerships.

Charm Therapeutics
Company
Industry:
Robotics
Location:
Glasgow, UK
Year
2023
,
2025
,

Background

Revolutionizes drug discovery by compressing months-long synthesis timelines into days through AI-powered robotic chemistry.

Chemify
Company
Industry:
Robotics
Location:
Glasgow, UK
Year
2023
,
2025
,

Background

Revolutionizes drug discovery by compressing months-long synthesis timelines into days through AI-powered robotic chemistry.

Corvium
Company
Industry:
Food Tech
Location:
Washington, DC
Year
2014
,
2016
,

Background

Acquired by Neogen, a cloud based software that helps users implement food safety systems that reduce risk and elevate compliance.

Disarm Therapeutics
Company
Industry:
BioTech
Location:
Boston
Year
2018
,

Background

Acquired by Eli Lilly, targets SARM1 to halt neurodegeneration in ALS, MS, and neuropathy, massive underserved markets where no curative solutions currently exist.

eGenesis
Company
Industry:
BioTech
Location:
Boston
Year
2018
,

Background

Developed, EGEN, s a proprietary gene-editing and genome engineering platform to create human-compatible organs and cells from pigs, aiming to eliminate transplant waitlists and reduce the need for lifelong immunosuppression.

Elicio Therapeutics
Company
Industry:
BioTech
Location:
Boston
Year
2015
,

Background

Advancing lymph-node-targeted mKRAS cancer vaccines to treat high-need pancreatic and colorectal tumors driven by mutations found in a quarter of solid cancers.

Envisagenics
Company
Industry:
BioTech
Location:
New York
Year
2019
,
2020
,

Background

Unlocks disease-specific RNA splicing isoforms through their AI platform, SpliceCore, opening entirely new therapeutic modalities for oncology and neurodegeneration.

Exact Sciences
Company
Industry:
BioTech
Location:
Wisconsin
Year
2018
,

Background

Developed a multi-cancer early detection test, capitalizing on the billion-dollar shift toward precision medicine of preventing, predicting and guiding personalized treatment.

Frontier Medicines
Company
Industry:
BioTech
Location:
San Francisco
Year
2018
,

Background

Combines chemoproteomics, covalent chemistry and machine-learning to uncover druggable sites on previously “undruggable” proteins and develop precision small-molecule therapies.

Herophilus/System 1
Company
Industry:
BioTech
Location:
San Francisco
Year
2018
,
2019
,
2021
,
2022
,

Background

Combines human brain models, scalable biology, and machine learning to decode neurological disease and discover novel therapeutics.

Juul
Company
Industry:
Consumer Products
Location:
San Francisco
Year
2017
,

Background

Juul develops and sells nicotine vapor devices designed as an alternative to traditional cigarettes.

LabGenius
Company
Industry:
BioTech
Location:
London, UK
Year
2024
,

Background

Uses machine-learning, high-throughput automation, and synthetic biology to engineer next-generation therapeutic antibodies via its EVA™ platform.

MC10
Company
Industry:
Digital Health
Location:
Boston
Year
2013
,
2015
,

Background

Now part of Medidata Solutions, MC10 develops ultra-thin, flexible electronics that integrate with the body to improve quality of life.

Meliora Therapeutics
Company
Industry:
BioTech
Location:
San Francisco
Year
2022
,

Background

Leverages its machine-learning AnchorOmics platform to develop small-molecule therapies for high-value cancer targets.

Metabomed
Company
Industry:
BioTech
Location:
New York
Year
2020
,

Background

Develops small-molecule therapies that target cancer-specific metabolic pathways identified through its proprietary computational, genomic, and metabolomic platform.

Momentous Therapeutics
Company
Industry:
BioTech
Location:
Cambridge, UK
Year
2024
,

Background

Drugging the biochemical centre of life.

Neumora Therapeutics
Company
Industry:
BioTech
Location:
Boston
Year
2018
,

Background

Develops precision medicines for neuropsychiatric and neurodegenerative diseases, targeting novel CNS mechanisms with best-in-class pharmacology and leveraging biological insights to identify the right patient populations.

Ochre Bio
Company
Industry:
BioTech
Location:
Oxford, UK
Year
2023
,

Background

Now in a licensing agreement with GSK, Ochre Bio uses AI-driven human-liver datasets and RNA therapeutics to develop precision medicines for chronic liver diseases.

Oncorus
Company
Industry:
BioTech
Location:
Boston
Year
2018
,

Background

Develops IV-administered, self-amplifying RNA therapeutics designed to kill tumor cells and activate multiple arms of the immune system for transformative cancer outcomes.

Pax Labs
Company
Industry:
Consumer Products
Location:
San Francisco
Year
2017
,

Background

Creates precision-engineered, high-quality cannabis devices and products that elevate the consumer experience, backed by nearly two decades of innovation and a commitment to being Plastic Negative.

Prosetta Biosciences
Company
Industry:
BioTech
Location:
San Francisco
Year
2016
,

Background

Uses a proprietary cell-free protein synthesis and assembly platform to discover small-molecule modulators of multi-protein complexes across infectious and degenerative diseases.

Recursion
Company
Industry:
BioTech
Location:
Salt Lake City
Year
2022
,

Background

Industrializes drug discovery through high-throughput automation, massive biological datasets and AI-driven models to decode biology and discover first-in-class therapeutics for multiple disease areas.

ReDesign Science
Company
Industry:
BioTech
Location:
New York
Year
2022
,

Background

Combines physics-based molecular simulation with deep learning to generate novel Protein Interaction Modulators for oncogenic and inflammatory diseases.

Relation Therapeutics
Company
Industry:
BioTech
Location:
London, UK
Year
2021
,
2022
,

Background

Leverages single-cell multi-omics, functional assays and machine-learning to discover and develop transformational medicines based on deep biological relationships.

Revolo Biotherapeutics
Company
Industry:
BioTech
Location:
Washington, DC
Year
2022
,

Background

Develops first-in-class protein and peptide therapies that reset, rather than suppress, the immune system to deliver durable remission across autoimmune and allergic diseases.

Sana/Cobalt Biomedicines
Company
Industry:
BioTech
Location:
Seattle
Year
2018
,

Background

(Merged entity) Advances in-cell delivery of gene and protein therapeutics using engineered fusogen technology to treat diseases at their cellular origin.

Sienna Labs
Company
Industry:
BioTech
Location:
San Diego
Year
2014
,

Background

Biophysics company that developed Targeted Plasmonic Therapy (TPT) using proprietary plasmonic nanoparticles combined with existing energy devices to treat acne and remove light-pigmented hair.

Soft Robotics/Oxipital
Company
Industry:
Robotics
Location:
Boston
Year
2013
,
2015
,
2017
,

Background

Dominates AI-powered machine vision for manufacturing, capturing the industrial automation supercycle across food, agriculture, and consumer goods.

Source/Zero Mass Water
Company
Industry:
Sustainability
Location:
Phoenix
Year
2016
,

Background

Designs solar-powered atmospheric water generators that convert air and sunlight into clean drinking water for homes, schools and communities.

Third Harmonic Bio
Company
Industry:
BioTech
Location:
San Francisco
Year
2017
,

Background

Focused on advancing medicine for dermal, respiratory, and gastrointestinal inflammatory diseases through novel, highly selective small-molecule inhibitors of KIT

Thrive Bioscience
Company
Industry:
BioTech
Location:
Boston
Year
2015
,

Background

Develops automated live-cell imaging systems and analytics that generate high-resolution, reproducible, AI-ready datasets, transforming how scientists capture and interpret dynamic cell biology.

Tizona Therapeutics
Company
Industry:
BioTech
Location:
San Francisco
Year
2017
,

Background

Develops targeted immunotherapies that modulate immunosuppressive cell populations and pathways to restore anti-tumor immunity or prevent autoimmune attack.

Toreador Therapeutics
Company
Industry:
BioTech
Location:
San Francisco
Year
2024
,

Background

Develops next-generation multispecific cancer therapies by combining DNA-based super-resolution microscopy with T-cell engagers, bispecifics/multispecifics, ADCs and radiopharmaceuticals for enhanced selectivity.

Trishula Therapeutics
Company
Industry:
BioTech
Location:
San Francisco
Year
2020
,

Background

Develops cancer therapies, primarily targeting gastric and pancreatic cancer with its lead candidate, TTX-030, an anti-CD39 antibody.

Tyra Biosciences
Company
Industry:
BioTech
Location:
San Diego
Year
2019
,

Background

Develops next-generation FGFR-targeted precision medicines using a structural design platform that anticipates resistance mutations to accelerate oncology and genetic disease therapies.

Variant
Company
Industry:
BioTech
Location:
Seattle
Year
2020
,

Background

Harnesses human genetic diversity from underrepresented populations worldwide across 20+ research partnerships to identify disease-driving genes using AI/ML, creating a pipeline of "impossible-to-find" therapeutics for fibrotic, kidney, and liver diseases.

Visla/Braid Health
Company
Industry:
Health Tech
Location:
San Francisco
Year
2020
,

Background

Delivers an AI-enabled diagnostic collaboration platform that pairs board-certified radiologists with intelligent imaging workflows to accelerate and enhance medical image interpretation.

Werewolf Therapeutics
Company
Industry:
Location:
Boston
Year
2021
,

Background

Designs "shape-shifting" cytokine drugs using PREDATOR platform that activate only in tumors, unleashing validated immune mechanisms while preventing toxic side effects in peripheral tissue.

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Frequently Asked Questions

FAQ

Discover our most frequently asked questions

Occam Global invests at the intersection of AI and deep technology, areas where leadership quality can accelerate discovery and commercial success. We back companies solving meaningful problems in life sciences, biotechnology, precision medicine, advanced analytics, robotics, manufacturing and defense innovation.

Most investors provide capital. We provide capital and leadership to drive innovation forward. Our dual capability — venture investing and executive recruiting — enables portfolio companies to scale with both funding and the right executive talent. We help founders build boards, strengthen leadership teams, and scale operations intelligently.

We primarily invest in early to growth-stage companies (Seed through Series B). However, we occasionally participate in later rounds when strategic leadership placement or operational guidance can create disproportionate value.

Investment size varies depending on stage and strategic alignment, but typically ranges from $5M-$20M. More importantly, our engagement doesn’t end with capital — we stay deeply involved in leadership and growth execution.

Occam does both. We frequently co-invest alongside institutional and strategic investors who share our conviction in building durable, high-performance companies. When we lead, we often complement our investment with executive search support to strengthen leadership readiness post-funding.

In addition to traditional investor support, we provide executive search and leadership advisory, organizational design and team scaling guidance, and access to our global network of operators, scientists, and and investors

We back founders who pair scientific depth with strategic clarity and are willing to operate in complex, regulated, or frontier markets. We’re especially drawn to those with unconventional paths to entrepreneurship and original, creative approaches to solving persistent problems.

Not exactly. Occam Global operates as a strategic venture platform combining elements of venture capital, executive search, and leadership advisory. Our capital goes further because it’s matched with talent and operational guidance and mentorship.